Probiotics are effective treatments for IBS, although which individual species and strains are the most beneficial remains unclear. – in The American Journal of Gastroenterology 109, 1547-1561 (October 2014), review of 43 randomized controlled trials.
There is strong evidence for probiotics as a treatment for digestive issues such as the Irritable Bowel Syndrome. Recent reviews of many randomized controlled trials have shown that symptoms such as bloating, pain and stool inconsistencies can be improved significantly by taking probiotics.
However, there is no single magic bacterial strain that will solve your issues or a special “proprietary formula”.
In an industry overrun with false labels and magic pills we will give you all the information you need, as well as the science behind it.
The truth is that scientists know that there are bacterial strains showing effects, but it is unclear which combination of strains can help you as an individual person with your unique metabolism and microbiome. This problem can only be solved by getting insights into your unique gut flora and symptoms. Which is what we do.
It can take years until the latest research makes it into a new product. We are working closely with the leading doctors and scientists in digestive health. Our experts help us to enrich our algorithms with scientific evidence.
For the manufacturing of our probiotics we are cooperating with manufacturers producing probiotics at the highest quality standards. From the patented capsules to scientifically researched bacterial strains – we can make sure that they match the highest quality possible. The composition of our bacterial strains is unique and not comparable to any probiotic product currently on the market, because it’s based on latest research and analysis of the data of 1000s of users using the Cara App.
We’ve selected bacterial strains which have been scientifically shown to have highly positive effects from the world’s leading probiotic laboratories. There is scientific evidence in a variety of fields.
There is a strong connection between our gut (nervous system) and our brain. Studies have shown that probiotic intake can reduce depression scores significantly in patients with both digestive and mental issues.
Probiotics have shown an alleviation of symptoms, because some strains support lactose breakdown in the small intestine and an improved tolerance in the large intestine
Probiotics help to prevent colds. A review of 12 controlled trials showed that around half as many study participants became ill if they had taken probiotics and that probiotics made it possible to reduce the duration of illness by almost two days. Less antibiotics were prescribed for those who took probiotics.
Lactobacillus is a well known genus living in the human gut (and also at a number of other body sites). This bacterium is part of a group of bacteria that produce lactic acid. In fact, they convert sugars to lactic acid. Studies showed that Lactobacillus can help people with Lactose Intolerance. There is an increased breakdown of lactose in the small intestine by probiotics (probiotic cultures themselves release the lactase enzyme which breaks down lactose) and a positive effect on the microflora in the large intestine by which means the lactose is better tolerated and more easily absorbed.
Lactobacillus can inhibit the growth of the fungal pathogen candida albicans. Studies have shown that people with digestive issues often have a low level of lactobacilli and bifidobacteria.
References: 1, 2, 3, 4, 5, 6, 15, 21, 24, 25, 26, 28, 29
The genus Bifidobacterium is an ubiquitous inhabitant of the human gut. Bifidobacteria can produce lactic acid and have the ability to ferment carbohydrates. In clinical use, Bifidobacteria are often used to improve rates of remission in ulcerative colitis. Several benefits of the Bifidobacterium as a probiotic supplement have been found, such as reducing symptoms of the Irritable Bowel Syndrome, helping people with lactose intolerance and reduction of stool inconsistencies.
References: 21, 22, 27
Streptococcus is widely known as a dangerous genus, causing infections like pharyngitis and many others. However, the detail makes the difference because there is a complete harmless species called streptococcus thermophilus which has been used for years in the food industry to produce yoghurt and cheese. Usage in probiotics has shown beneficial effects for stool regulation, breakdown of lactose and symptom reduction in IBS patients.
References: 30, 31, 9, 22
Different to other probiotics saccharomyces is not a bacterium, but a yeast. Species like saccharomyces boulardii have been studies extensively and have been shown to be beneficial in different combination of symptoms. It helps to regulate stool frequencies in IBS patients and people with infectious diarrhea. There is also early research for treating people suffering from inflammatory bowel disease or limiting side effects of a helicobacter eradication. Don’t worry about fungal overgrowth. Except for cases with complete immune suppression there is no reason to worry about side effects. Even HIV patients can benefit from saccharomyces to limit diarrhea as a symptom.
References: 23, 28, 32, 33, 34, 35
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12) Pinto-Sanchez, Maria Ines, et al. “Probiotic Bifidobacterium longum NCC3001 Reduces Depression Scores and Alters Brain Activity: a Pilot Study in Patients With Irritable Bowel Syndrome.” Gastroenterology (2017).
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